Sepsis Diagnosis With Telemedicine: A Scoping Review
DOI:
https://doi.org/10.30953/thmt.v11.726Keywords:
diagnosis, telehealth, telemedicine, sepsisAbstract
Background: Sepsis is a life-threatening condition requiring early recognition to reduce morbidity and mortality. As telemedicine continues to grow as a mode of healthcare delivery, understanding its role in sepsis diagnosis is becoming increasingly important. However, evidence relating to sepsis diagnosis in the virtual space is limited across the literature. This scoping review aims to explore and synthesise the available evidence on factors inherent to telemedicine consultations that may influence sepsis diagnosis.
Methods: This scoping review was conducted in accordance with JBI methodology. MEDLINE, Embase and Cochrane databases were searched for peer-reviewed publications of any study design, published in English and after 2000. Our inclusion criteria included patients of any age, assessed via any telemedicine modality and subsequently diagnosed with sepsis. The settings included were primary care and emergency care. Data were extracted into tabular and narrative formats.
Results: A total of eight studies were included, demonstrating considerable heterogeneity in study design, telemedicine modality and setting. Several consistent themes that influenced virtual sepsis diagnosis emerged across the included studies. Patient factors included vague and non-specific symptom presentations, recognition of acute deterioration and the presence of risk factors. Clinician factors included provider experience, provider type, diagnostic uncertainty and history-taking practices. Consultation factors included the telemedicine modality, consultation duration and limited capacity to perform physical examination.
Conclusions: Telemedicine may play a complementary and synergistic role in the sepsis diagnosis pathway, however, it may be amplifying existing diagnostic challenges. Integration of multiple clinical indicators, help-seeking behaviours and appropriate escalation are likely to support sepsis diagnosis and enhance patient safety in virtual care. Future research should focus on evaluating the diagnostic accuracy of telemedicine for sepsis diagnosis and the development of a telemedicine-specific sepsis screening tool.
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Copyright (c) 2026 Bethany S. Hansen, BBiomedSc, James H. Boyd, BSc (Hons), PhD, Jennifer Hutton, MBChB, MPH, FACEM

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